Omidon Suspension 100ml

✔️ Uses of Omidon Suspension

• Treats nausea and vomiting

✔️ How does Omidon Suspension work?

Omidon Suspension has an anti-emetic property that acts by blocking a chemical messenger in the brain called dopamine, which transfers information through nerve endings. Suspension functions by inhibiting the muscle contraction that occurs naturally in the digestive system and enhances the peristaltic movement in the food pipe which helps in facilitating the digestion time faster, this causes calming down effect, thereby relieving nausea or vomiting sensation.

✔️ Side Effects of Omidon Suspension

Common side effects:

• Dry mouth

Uncommon side effects:

• Feeling anxious
• Feeling drowsy
• Headache
• Diarrhea
• Itchy skin, rash
• Unusual production of breast milk in men and women
• Painful or tender breasts
• Lowering of sexual desire in men

Rare side effects:

• Severe allergic reaction with symptoms such as swelling of the hands, feet, ankles, face, lips, and throat, which may cause difficulty in swallowing or breathing
• An itchy lumpy rash (hives), nettle rash (urticaria)
• Uncontrolled movements, including irregular movements of the eyes, unusual movement of the tongue, and abnormal posture (e.g., twisted neck)
• Fast, unusual heartbeat
• Seizures (fits)

✔️ Quick Suggestions:

• Omidon Suspension should be taken before meals as per the dose and duration prescribed by the doctor.
• A dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake, and sugarless candy may help.
• If needed, Omidon Suspension can be given along with fever medicines unless your child’s doctor has told you not to.
• Do not mix Omidon Suspension with any herbal or ayurvedic medicines as they can harm you.
• Give Omidon Suspension for the current illness. Do not save medicines to treat future symptoms
• If you are not sure a medicine is working, do not stop the medicine abruptly by yourself. Call your child’s doctor for advice. Meanwhile, continue with the medicine.

✔️ Indication of Omidon Suspension

Omidon Suspension is used for the Treatment of-

• Gastroesophageal reflux disease (Acid reflux)
• Indigestion
• Nausea
• Vomiting

✔️ Pharmacology

Domperidone is a peripheral dopamine-receptor blocker. Its main mechanism of action is to block dopamine receptors in the gastrointestinal tract, specifically in the Chemoreceptor Trigger Zone (CTZ) and the stomach. By blocking these dopamine receptors, domperidone increases esophageal peristalsis (contractions of the esophagus), enhances gastroduodenal coordination, and reduces the pressure of the lower esophageal sphincter.

The overall effect of these actions is the facilitation of gastric emptying and a decrease in the transit time of the small bowel. This leads to improved motility and movement of food through the digestive system.

It's important to note that domperidone does not cross the blood-brain barrier as effectively as other dopamine antagonists, such as metoclopramide. Therefore, its action is primarily limited to the gastrointestinal tract, making it useful for the treatment of nausea, vomiting, and disorders related to delayed gastric emptying.

✔️ Dosage & Administration of

1. General Dosage:

• Adults: The usual oral dose for adults is 10-20 mg (1-2 tablets or 10-20 ml suspension) taken every 6-8 hours daily. The maximum daily dose should not exceed 80 mg.
• Children: The recommended dose for children is 2-4 ml suspension or 0.4-0.8 ml pediatric drops per 10 kg body weight, every 6-8 hours daily.

1. Dyspeptic Symptoms:

• Adults: For dyspeptic symptoms, adults can take 10-20 mg (1-2 tablets or 10-20 ml suspension) every 6-8 hours daily.
• Children: The recommended dose for children with dyspeptic symptoms is 0.2-0.4 mg/kg (2-4 ml suspension or 0.4-0.8 ml pediatric drops per 10 kg body weight) every 6-8 hours daily.

1. Acute and Sub-acute Conditions (Nausea and Vomiting):

• Adults: In cases of acute and sub-acute nausea and vomiting, adults can take 20 mg (2 tablets or 20 ml suspension) every 6-8 hours daily.
• Children: The recommended dose for children experiencing acute and sub-acute nausea and vomiting is 0.2-0.4 mg/kg (2-4 ml suspension or 0.4-0.8 ml pediatric drops per 10 kg body weight) every 6-8 hours daily. The maximum treatment period for acute nausea and vomiting is 12 weeks.

Take Omidon Suspension as advised by your physician. Shake well before use. Your doctor will decide the appropriate dose and duration of Omidon Suspension for you depending on your age, body weight, and disease condition.

✔️ Interaction

It's important to inform your doctor about all the medications you are taking, including over-the-counter drugs, herbal supplements, and any underlying medical conditions you may have. Omidon Suspension may interact with various medications, and your doctor needs to consider these interactions to ensure your safety and optimize the effectiveness of the treatment.

Some of the medications that may interact with Omidon Suspension include:

1. Medicines used to treat fungal infections (e.g., ketoconazole, fluconazole, voriconazole)
2. Medicines used to treat bacterial infections (e.g., erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine)
3. Medicines used to treat heart problems or high blood pressure (e.g., amiodarone, dronedarone, quinidine, disopyramide, bepridil, dofetilide, sotalol, diltiazem, verapamil)
4. Medicines used to treat psychoses or depression (e.g., haloperidol, pimozide, sertindole, citalopram, escitalopram)
5. Medicines used to treat gastrointestinal disorders (e.g., cisapride, diphenyl, dolasetron, prucalopride)
6. Medicines used to treat allergies (e.g., mequitazine, mizolastine)
7. Medicines used to treat malaria (specifically halofantrine)
8. Medicines used to treat AIDS/HIV (e.g., ritonavir, atazanavir)
9. Medicines used to treat cancer (e.g., toremifene, vandetanib, vincamine)
10. Medicines used to treat drug addiction (e.g., methadone)

Additionally, Omidon Suspension may interact with grapefruit juice, alcohol, and tobacco, so it's advisable to avoid them while taking this medication.

Furthermore, caution should be exercised when using Omidon Suspension in patients with pre-existing heart, kidney, or liver disease, brain tumors, a history of gastrointestinal bleeding, or any bowel-related problems.

It's important to follow your doctor's instructions and inform them about all the medications you are taking to ensure a safe and effective treatment plan.

If you have any further questions or concerns, please consult your healthcare provider.

✔️ Contraindications

Domperidone is not recommended for patients who have a known hypersensitivity to the drug or for neonates. When gastrointestinal stimulation is potentially dangerous, such as gastrointestinal hemorrhage, mechanical obstruction, or perforation, do not use domperidone. Patients with a prolactin-releasing pituitary tumor are also advised against taking it (prolactinoma).

✔️ Pregnancy & Lactation

While the safety of Domperidone has not been definitively established during pregnancy, it is generally not recommended for use in pregnant women. This caution is primarily due to the lack of sufficient studies on pregnant women to determine its potential teratogenic effects on the fetus. However, animal studies have not shown any teratogenic effects.

On the other hand, Domperidone has been used to help manage galactorrhea (spontaneous milk production) and to increase milk production in postpartum women who are breastfeeding. It is known to be excreted in breast milk but in minimal amounts that are not considered harmful to the nursing infant.

It's important to note that individual circumstances and medical advice may vary, and it is always recommended to consult with a healthcare professional, such as your doctor or obstetrician, before taking any medication during pregnancy or while breastfeeding. They can provide personalized guidance based on your specific situation and weigh the potential benefits against the possible risks.

If you have any further questions or concerns about the use of Domperidone during pregnancy or while breastfeeding, it's best to discuss them with your healthcare provider.

✔️ Precautions & Warnings

Allergy: Do not take Omidon Suspension if you are allergic to any of its components. It's important to check the ingredients and consult your doctor if you have any known allergies.

Liver or kidney problems: Inform your doctor if you have liver or kidney problems, as special caution may be required when taking Omidon Suspension in such cases. Your doctor will assess the risks and benefits of the medication for you.

Increased risk of heart rhythm disorders: Prolonged use of Omidon Suspension, especially at doses higher than 30 mg daily, may be associated with an increased risk of heart rhythm disorders (arrhythmias) and cardiac arrest, particularly in elderly individuals (over 60 years old). If you experience symptoms such as palpitations, difficulty breathing, or loss of consciousness, seek immediate medical attention.

Anti-fungal medicines, heart problems, and AIDS/HIV: Inform your doctor if you are using anti-fungal medicines or if you have heart problems or AIDS/HIV. These conditions may require special consideration when taking Omidon Suspension, and your doctor can provide appropriate guidance.

Pregnancy and breast-feeding: Domperidone is generally not recommended during pregnancy and breastfeeding. However, in certain cases, it may be used to increase milk supply during breastfeeding if deemed necessary by a physician. It's important to consult your doctor for advice before taking Suspension if you are pregnant or breastfeeding.

Adolescents and children: Omidon Suspension should not be given to adolescents (children aged 12-18 years) who weigh less than 35 kg. Safety and dosage considerations may vary based on the individual's weight and age, so it's important to follow your doctor's instructions.

✔️ Storage Conditions

Store at or below 30°C, away from light and moisture. Keep out of reach of children.